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Saint Paul University provided supplementary funding.
Although different experts do not always provide consistent annotations (Supplementary Fig. S7), we are also investigating a multitask learning model that could potentially have better prediction accuracy for each of those experts.
For clarity throughout this report, we designate identified Hsp70 genes in accordance with the names of their S. cerevisiae homologs, with the specific genomic annotations for each identified Hsp70 gene provided in supplementary figure S1, Supplementary Material online.
Our raw data for E. coli, including functionality annotation and ZΔ G values, are provided as supplementary table 2, Supplementary Material online.
Further details and annotations of our lincRNA locus models, together with whether these are validated by qRT PCR, are provided in supplementary table 1 (Supplementary Material online).
The current detailed annotations are provided in Supplementary Table 3. > We have verified the expression of seven of these re-annotated genes by PCR (Table 6 and Fig. 3).
Details of the identification and annotation of previously undiscovered or unannotated proteins in ciliate mitochondrial genomes and the Nycotherus hydrogenosomal genome are provided in supplementary table 1 (Supplementary Material online).
A list of the additional RNA genes that have been reported previously in the literature, but have not yet been incorporated or are misannotated in the GeneDB genome annotation is provided as Supplementary Material (Additional File 2).
Detailed evaluation and annotation guidelines are provided as Supplementary Materials.
The annotation libraries are provided in Supplementary Table S1 using a threshold e-value of 10−5.
A detailed listing and description of all included annotation sets is provided in Supplementary Material, Table S12.
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