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Of the numerous human genetic diseases, LSDs likely provide the highest chance for the clinical success of gene therapy strategies given contemporary understandings of the limitations of gene therapy approaches.
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This strategy will provide the highest chance of identifying genetic predictors of responsiveness to folate whilst simultaneously provide us with a resource, as knowledge of the genetics of these pathways increases, for future refinement and identification of other associations.
Taking these data together, we propose a model in which both neuroinflammation and oligodendrocyte dysfunction provide the highest risk for axonal loss, with demyelination surprisingly improving the chance of axon survival, at least in the short term.
Those additional notations provide a higher chance for successful name matching.
Identifying such users is relevant for allocating tasks in the community, as these are the contributors with the highest chance of providing a timely response to a request or suggestion.
Surgical procedures provide the best chance for cure and long-term survival in non-small cell cancer (NSCLC).
Surgery offers the highest chance of oncologically complete resection for these malignant lesions.
In the Netherlands, apixaban had the highest chance (37 %) of being cost effective at a threshold of €20,000; in the UK, this chance was 41%% for dabigatran.
Furthermore, the TiO2 graphene complex nanopaper based PEC biosensor in this study was anticipated to provide the chance for the design of high-performance PEC biosensors for the detection of other enzymes and biomolecules.
There are geographical, cultural and historical differences between the two sites, which may result in different learning atmosphere and provide the chance for students to have a high degree of contact with patients from different cultural backgrounds.
Early detection still provides the best chance for successful treatment.
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