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We have already developed a number of phylogenetic predictions that are just beginning to provide powerful tests of coevolutionary hypotheses.
Large and well-resolved phylogenies that incorporate divergence times provide powerful tests of a wide range of hypotheses whilst accounting for the effects of shared evolutionary history [ 13, 15].
This study provides rare empirical data on variation in early life history traits in a population network of a salmonid, and large-scale breeding and transplantation experiments like ours provide powerful tests for local adaptation.
Although the existing approaches provide powerful tests that can incorporate information on allele frequencies and prior biological knowledge, differences in the spatial clustering of rare variants between cases and controls cannot be incorporated.
Site-directed mutagenesis reveals residues that give large functional effects upon mutation, and double mutant cycles provide powerful tests for energetic dependence vs independence between two residues (Carter et al., 1984; Hertel et al., 1994; Horovitz, 1996; Narlikar et al., 1999).
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Further studies examining the mode of germ cell specification in several of the above lineages will provide powerful data to test the intriguing notion that the acquisition of predetermined germ cell specification permits or even drives the loss of POU5F1[ 32].
Recent advances in molecular epidemiology can also provide powerful tools for testing predictions of how pathogens spread and evolve, through the capacity to characterize pathogen genomes for similarities and differences across animal and human populations (Parkhill and Wren 2011).
For the Forest City Ratner Companies, the developer of Beekman Tower, the project will test the idea that an architect can provide powerful (and expensive) modeling software to help keep costs down.
Artificial intelligence techniques provide powerful tools for processing information stored in archives of safety-related data, such as measurements, documents, and test data.
Both provide powerful ways of reusing code.
Microscale technologies provide powerful experimental tools for a wide range of relevant applications in stem cell research, including high-throughput screening of large numbers of test samples.
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