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Here, we tested whether genomic gains in six specific loci, TP63 on 3q28, EGFR on 7p12, MYC on 8q24, 5p15.2, and centromeric regions for chromosomes 3 (CEP3) and 6 (CEP6), may provide further value in the prediction of lung cancer.
Integrated PET/CT can provide further value especially in the postoperatively distorted liver with scar tissue and artificial materials, where sensitivity and specificity are relatively low for both CT and MRI [ 19, 20].
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Person-level health and sociodemographic variables were then fitted sequentially to examine whether they could provide further explanatory value.
The imbalance in treatment modalities but similar outcome suggested that concurrent chemotherapy in the setting of conformal radiation therapy using IMRT after neoadjuvant chemotherapy might not provide further therapeutic value, even in patients with more advanced disease and poor prognostic factor (i.e., male gender).
The cases and discussion below provide further reflection on the value of integrated HIA/EIA in the United States.
Our findings provide further evidence for the value of phenotype-associated marker panels over single molecules in predicting progression in pTa and pT1 bladder cancers.
If future studies confirm this it would provide further evidence of the value of this form of intervention and could support the concept that relatively early intervention to increase physical activity in COPD patients is disease modifying [ 9].
In this issue, Bulkmans et al (2005) and Grainge et al (2005), using two different study designs, provide further evidence of the value of adding HPV testing to cervical cytology in screening programmes.
Future screening rounds will determine the optimal frequency of PSA testing, determine the utility of PSA screening in BRCA1 carriers, and provide further data on the value of annual screening in BRCA2 carriers.
Other surveys provide further evidence that parents value their role in decisions about trial entry – over 90% say they do not want the doctor or nurse to decide on their behalf [ 21, 22, 8].
Overall, our results provide further evidence for the value of quality improvement approaches in health care service delivery in low-income countries as a core part of the repertoire of strategies aimed at accelerating efforts towards achievement of the health related millennium development goals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com