In addition to cation-π interaction, amino-aromatic interaction could also contribute to the formation of R5-Y9 side-chain interandions, and Y9 could be involved in long-range interaction with the negatively charged side-chain of E2 providing further specificity to the assembly.
These findings provide further support for the specificity of the 17-gene classifier to detect melanoma specifically.
Together, these findings provide further insight in the specificity of sex differences in spatial memory and in the functional architecture of spatial memory.
Here, we demonstrate that their uptake is not sensitive to changes in intracellular GSH concentration within the range investigated and provide further confirmation of their specificity for tissue which is insufficiently oxygenated.
Thus, collectively, these results do not support a mechanism whereby VCD causes ovotoxicity via generalized activation of primordial follicle recruitment, but instead provide further support for the specificity of other intracellular mechanisms involved in VCD-induced ovotoxicity.
Complementing these studies with a quantitative mesoscopic modality such as fluorescent-mediated molecular tomography (FMT) would provide further insight into the specificity, scope, and magnitude of the response.
Our data provide further insight into the specificity of Agu115 and a deeper understanding of the enzymatic pre-treatments required for the full degradation of GAX.
We have revised the text to provide further clarity regarding the specificity of the genetic manipulations that allow us to conclude that it is Wfs1 dysfunction specifically in the mPFC that alters stress-induced depressive behaviors.
To provide further evidence for the specificity of the antibody, we probed Western blots of MCF-7 cells overexpressing PRL-3 with the PRL-3 antiserum as follows: MCF-7 cells were plated in six-well tissue culture plates at 70% confluency and cultured as previously described (Wülfing et al, 2005b).
