The full algorithm is provided for clarification in Algorithm 1 and works as follows: a direction model that has mixtures of von Mises distributions and as its input and outputs a set of clusters.
The purpose of this commentary is to accomplish the following: (i) highlight issues proposed for consideration in the ICH revision process, (ii) offer a rationale for why these issues may compromise the design of a testing protocol and/or the results of the testing program, and (iii) provide recommendations for clarification of the guideline.
Communication provides opportunities for clarification, for members to discuss improvement to an organization and impact of using different risk mitigation strategies.
Overall, the present study unravelled a novel function of HMGA2 in induction of apoptosis in human primary cell lines, and provided clues for clarification of the mechanistic action of HMGA2 in addition to its function as an oncoprotein.
1 In the current study, an education and support package for patients and carers that expanded upon the previously evaluated 'What you need to know about stroke' tailored booklet and provided opportunities for clarification and reinforcement of information both prior to, and following, discharge was developed.
However, given the opportunity that a telephone interview provides for questions and clarifications, these results may not directly relate to data collected by other means, such as written questionnaires.
But James Plastiras, a spokesman for the division in Albany, said that while the court ruling had spurred it to define the term, state officials still felt obligated to provide clarification for both tenants and owners.
Basically, the theory is vague; it does not provide clarification for specific scenarios and "did not provide a satisfactory pragmatic approach required by business managers in order to implement CSR" (Claydon, 2011, p.409).
Our results provide some clarification for the reasons behind the inconsistencies.
The data presented here provide some clarification for the basis of that apoptosis: neural stem and progenitor cells lacking Dicer and microRNAs can self-renew, but undergo apoptosis when they attempt neurogenesis.
The PK results did not provide a clarification for the observed enhanced toxicity.
