Analysis of defined cell populations will provide cornerstones to our view of systems biology but will not provide sufficient insight into the networks of functional units consisting of different interacting cells and organ systems.
December 8 2010 December 9 201010 The big autumn sales of antiquities at Christie's and Sotheby's provide the cornerstone of the week.
This could mean charging the public for access to the New Forest and will almost certainly involve selling off parts of the estate which currently provide the cornerstone of commoning.
SKOS vocabularies provide a cornerstone for linking information on the Web.
While test collections provide the cornerstone for Cranfield-based evaluation of information retrieval (IR) systems, it has become practically infeasible to rely on traditional pooling techniques to construct test collections at the scale of today's massive document collections (e.g., ClueWeb12's 700M+ Webpages).
With the advent of immuno-oncology drugs based on immune checkpoint blockade, a clear rationale for synergy between the two approaches, and initial pre-clinical and clinical data suggesting this to be the case, it might be expected that oncolytic immunotherapy combined with checkpoint blockade will provide a cornerstone of future cancer treatment.
Using these simulations, Doncic and colleagues lay out a simple scheme to simulate checkpoint signalling and provide the cornerstone in quantitative modelling of the spindle assembly checkpoint.
The results of this trial should be broadly generalisable and provide a cornerstone for future early mobilisation research in surgical ICU.
In our experience this has led to an increase in interest for clinical practice in specific medical fields and less for pathology which should actually provide the cornerstone of the students' knowledge of disease whatever specialization he/she may choose.
Nonetheless, a similar mind set of regular review in a specialist centre, with targeted multisystem care, and an aggressive approach to airway clearance and management of infections, should provide the cornerstone of therapy.
