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Biodegradable porous polymer scaffolds are widely used in tissue engineering to provide a structural template for cell seeding and extracellular matrix formation.
Our combined findings provide a structural template for the common functional architecture of the three major replicative DNA polymerases.
Finally, we provide a structural template for mutational studies directed towards defining the biological role of Tiam1/2 in activating Rac in cells and, ultimately, in whole animals.
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The bottom Cr2O3 layer provides a structural template for improving the crystallinity of VO2 and increasing the luminous transmittance of the structure.
While in dehydration-sensitive amphibians the stratum corneum consists of one or two cell layers, in mammals it is multilayered and provides a structural template for sealing lipids that perform a water barrier function.
Adenoviral VAI RNA binds tightly to JAZ and provides a structural template for the investigation of the mechanisms by which JAZ recognizes dsRNA.
Gene-activated matrix (GAM) blends these two strategies, serving as local bioreactor with therapeutic agents expression and also providing a structural template to fill the lesion defects for cell adhesion, proliferation and synthesis of extracellular matrix (ECM).
The α-ketoheterocycle functionality provides a moderately electrophilic ketone carbonyl with 'tunable' reactivity, as well as a structural template for introducing new interactions in the enzyme active-site cleft.
To provide a structural basis for these observations, we determined the structure of wt RB69pol with 3DA at position n – 1 of the template strand.
This may provide a structural basis for an active site.
Our data provide a structural rationale for these observations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com