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Bone scaffolds provide a structural support for tissue development.
These mesenchyme-derived cell lineages not only provide a structural support for the formation of the branched airways and the vascular networks, but may also regulate the growth of epithelial and endothelial cells by generating various morphogenic signals such as bone morphogenetic proteins (Bmps), fibroblast growth factors (Fgfs), and Wnts [ 1].
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Providing a structural support for the delivered cells appears important for cell based therapeutic approaches.
When coaptation is not possible in the repair of nerve injuries, a bridge of biomaterial scaffold provides a structural support for neuronal cell growth and guides nerve regeneration.
In addition to delivering bone as an organ, endochondral ossification provided a structural support for vertebrate limb development.
The suggested mechanisms of wound improvement when applying the ECM scaffolds alone are related to providing a structural support, stimulating angiogenesis, chemotaxis for endothelial cells, and release of growth factors [ 17, 18].
This indicates that the tantalum rod implant provides a meaningful structural support for the subchondral plate in addition to the core decompression achieved by the porous nature of the material.
Roots provide a structural and physiological support for plant interactions with the soil environment by conducting transport of water, ions and nutrients.
Actin filaments provide vital structural support for cellular shape and polymerization of actin at the leading edge is a fundamental process driving cell migration.
Lignin is also used in other cell types like sclerenchyma fibers that provide structural support for a plant and is a major constituent of wood.
Glial cells provide nutrients to neurons, protect the brain from infectious disease microbes and remove dead cells, help with brain development, insulate neurons from each other to allow efficient electrical signal transmissions and provide a source of structural support for neurons.
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