Sentence examples for provide a structural framework for from inspiring English sources
The crystal structures of the ClC channels of Escherichia coli and Salmonella typhimurium provide a structural framework for the entire family.
The structures allow a detailed rationale to be developed for the observed affinity of the PU3 class of compounds for HSP90 and also provide a structural framework for design of compounds with improved binding affinity and drug-like properties.
These findings together with previously reported data on wt and mutant p53 provide a structural framework for understanding p53 dysfunction as a result of oncogenic mutations and its rescue by suppressor mutations and for a potential drug design aimed at restoring wt activity to aberrant p53 proteins.
The models provide a structural framework for interpretation of the resulting functional analysis.
Our models provide a structural framework for interpreting experimental data and allow predictions of the TLR signal transduction process.
The data also provide a structural framework for tailoring powerful and selective M-channel modulators, including openers and blockers.
Cineradiographic (X-ray film) studies of the skeletal kinematics of lung ventilation in alligators and birds provided a structural framework for our reconstruction of the pterosaurian breathing pump [26], [27].
Analysis of this co-conserved pattern, in light of the wealth of structural and functional data available on ErbB kinases, suggests a model in which the identified residues contribute to ErbB kinase functional divergence by providing a structural framework for the JM and C-terminal tail to uniquely regulate ErbB kinase activity (Figure 9).
This study provides a structural framework for how a Swi2/Snf2 ATPase interacts with its substrate DNA:protein complex.
These domains consist of 2 45 motifs of 20 30 amino acids in length providing a structural framework for protein-protein interactions.
According to Cohen et al. [ 46], collagen is a principal component of connective tissue and provides a structural framework for the regenerating tissue.
