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Exact(5)
That would, however, provide a specificity of only ∼40% (Fig. 1 C).
As noted elsewhere, such case studies provide a specificity and transparency often absent from original descriptions of methods [ 9].
Both cutoff points are determined to provide a specificity level of 75% for the CA125 plus HE4 assay combination.
Using an Achilles T-score of −2.5 has been shown to provide a specificity of more than 90% for identifying only those subjects at high risk.
Therefore, it would seem that phosphorylation of the syndecan C2 domain can provide a specificity switch that goes some way to resolving the overcrowding issue.
Similar(55)
Three inhibitors, i.e. DAPT, L-685,458 and Compound E, inhibit the protease presenilin forming part of γ-secretase in general, whereas Compound W specifically blocks the processing of one substrate (APP), providing a specificity control.
This provides a specificity of 70% (see Table 5).
The mean specificity of the predictors was 98%, ten of which provided a specificity of 100%.
However, this provides a specificity of only 94% as several adenomas show SUV >2.31.
The underlying rationale of using this threshold is to establish a cut-off value providing a specificity of 97.5% [ 24, 25].
They also provided a specificity of 72%-100% and a sensitivity of 78%-100%, which possessed ability to discriminate ESHFMD from MHFMD with the AUC value of 0.76-0.82.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com