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One interesting possibility is that rare tRNAs are essential for the process of cotranslation folding, presumably because low abundance tRNAs provide a pause in translation that might be needed for proper folding (Thanaraj, 1996; Drummond and Wilke, 2008; Cabrita et al., 2010; Pechmann and Frydman, 2012).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com