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The specific aims of the project were to improve understanding of the role of low frequency and rare genetic variants in health and disease, and to provide a data resource that could be used on a long term basis by the research community.
Across a range of health conditions, large-scale clinical registries are being compiled to provide a data resource for quality assurance and research to inform clinical decision-making and health policy.
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The robust phenotyping and outcomes assessment of RCTs provides a data resource that may be used for testing future novel hypothesis.
The data described provide a comprehensive resource for the family-wide active site specificity portrayal of the human matrix metalloproteinase family.
The results identify both traditional and unexpected couplings and, in so doing, provide a data-driven resource to help inform dietary decisions.
CellMiner provides a data integration resource that includes multiple data types, platforms and cell lines from nine diverse cancer types.
Since the previous genetic information available was mostly ribosomal DNA, CamemBank01 provides a data mining resource for the dairy Fungi scientific community.
With the Zostera genome project under way and a large world-wide community working with seagrasses, it is imperative to provide a central data resource which is easily accessible by ecologists, evolutionary biologists and the like.
To provide an integrated data resource for further investigations, here we present a comprehensive database of dbPPT (database of Phosphorylation site in PlanTs, at http://dbppt.biocuckoo.org), which contains experimentally identified phosphorylation sites in proteins from plants.
Funded by the Wellcome Trust, the purpose of UK10K was two-fold: to investigate how low-frequency and rare genetic variants contribute to human disease, and to provide an enduring data resource for future research into human genetics.
Taken together, the dbPSP database provides a comprehensive data resource for further studies of protein phosphorylation in prokaryotes.
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