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Thus, AML-004 cells provide a continuous source of human cells for designing novel therapies for patients with T-lymphoblastic leukemia/lymphoma.
In vitro replicas of bone marrow can potentially provide a continuous source of blood cells for transplantation and serve as a laboratory model to examine human immune system dysfunctions and drug toxicology.
Whole cells have some NAD+ and NADP+ reserves that provide a continuous source of cofactors [7].
During incubation, this medium was refreshed every 2 days to provide a continuous source of Dox.
Sessile bacteria in biofilms provide a continuous source of planktonic bacteria as bacterial populations expand.
Mutations provide a continuous source of variation in natural populations, on which natural selection can act.
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Rather than giving rise to inviable cells, dicentric chromosomes provide a continuous source for new viable translocations and show signs of ongoing instability that leads to chromosome end erosion.
In the most recent study, the authors showed that hES cells spontaneously and continuously differentiate into hdFs, providing a continuous source of endogenous hES cell supportive factors, including IGF-2 and a host of TGF-β family of factors and other ligands [23].
Although biological thiol concentrations are typically higher than cellular H2S levels (high nM to low μM), the constant enzymatic production of H2S provides a continuous source of highly nucleophilic sulfide.
At the first sampling point (7d), the soil weight of moisture stressed plants weighed 210 ± 10 g less than unstressed plants that were provided a continuous source of water.
As such, natural products have provided a continuous source of novel chemical structures in the development of new drugs and approximately 119 pure compounds isolated from plants are being used as medicine throughout the world.
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