An ORA that takes advantage of known connectivity between gene set members provides a complementary view to the results provided by conventional enrichment methods (i.e. the Hypergeometric) and identify signaling events that are enriched for siRNA hits.
To provide a complementary view, logistic regression was used to examine the hypertension as an outcome, defined as using anti-hypertensive medication or having an SBP ≥ 140 mmHg and DBP ≥ 90 mmHg.
Apropos such potential, we provide a complementary view that considers capricious, if not nefarious use of CRISPR to modify biological entities (e.g., microbes, plants, animals, and humans) and/or produce bioagents that pose risk and/or threat to public safety (DiEuliis and Giordano, 2017).
Our findings provide a complementary view based on the cost side of participants' decision and have implications to other contexts where the project development is contingent on voluntary individual participation.
Thus, the domain genetic interaction is a new type of relationship among domains and can provide a complementary view about the relationships between domains.
The domain genetic interactions rarely overlap with the domain physical interactions from iPfam database and provide a complementary view about domain relationships.
These networks are derived from different sources of experimental data, or literature-based analysis, and provide a complementary view of drug mode of action.
Thus, EMS and SV-AUC techniques provide a complementary view of these complex interactions, which has allowed a thermodynamic dissection of these two IHF binding modes using model cos substrates.
Protein Interaction Networks can be of significant value in the analysis of a protein dataset as they may provide a complementary view of the biological pathways in which the proteins participate and reveal aspects of their functions [ 24, 25].
