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Importantly, this would provide a complementary mechanism to the generally envisioned linear nucleosome-to-nucleosome propagation of histone-modifying enzymes.
The cross-talk between H3K4me3 and H3K9me3 could provide a complementary mechanism to prevent the propagation of silenced chromatin states into transcriptionally active regions and vice versa.
PCSK9 inhibition has the potential to provide a complementary mechanism to other LLTs to significantly reduce LDL-C beyond the efficacy of statins [ 15, 17– 25].
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Since tumors with or without evidence of CNVs at NOTCH1 and JAG2 showed overexpression of the relevant gene products, we hypothesized that miRNAs could provide a complementary mechanism of NOTCH signaling deregulation in PGL.
Herein, we explore miRNA-based regulation of E1A expression as a complementary mechanism to promoter-based transcriptional control.
In fact, it provides a complementary mechanism involving large-scale groundwater discharges within the northern lowlands for the emplacement of fluids and sediments, which could have potentially contributed to the formation of these bodies.
The proteolytic GFAP fragment produced on caspase cleavage provides a complementary mechanism that could potentially alter GFAP filament organization and filament properties in astrocytes.
In this scenario, it is possible to hypothesize that ET-1 through ETBR can stimulate angiogenesis and lymphangiogenesis via HIF-1α providing an alternative or complementary mechanism to the tumor hypoxic microenvironment.
Additional animal models could provide a complementary tool to study the mechanisms of this disease that generate CNS injury.
These theoretical studies provide a complementary insight to experiment and suggest some new features.
The immunoconjugate could potentially provide a complementary treatment to ART to eradicate antigen-expressing T cells.
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CEO of Professional Science Editing for Scientists @ prosciediting.com