Sentence examples for proven to play a role from inspiring English sources

If the somatic SDHB mutations are proven to play a role in oxygen homeostasis in PBMCs and leukemic T cells, targeting of the SDH complex might provide new therapeutic tools against infections, leukemia and cancer.

To investigate the pathways of this process, we focused on telomere dysfunction, mitogen-activated protein kinases (MAPK) p38 and c-Jun N-terminal kinases (JNK), and p16INK4A which have proven to play a role in both doxorubicin-induced senescence in cardiomyocytes and in senescence in EPCs induced by other types of stress.

In a study of 23 patients with T2DM, SOD has been proven to play a role in modulating EPC function under hyperglycemic conditions [ 43].

Similarly, MEF2C has been proven to play a role in angiogenesis [ 24], and shown to be over-expressed in hepatocellular carcinoma [ 25].

In P. aeruginosa, type IV pili have proven to play a role in swarming motility, a form of migration over nutrient rich semi-solid surfaces [ 54, 55].

Finally, the subtle details of relevant regulatory processes (e.g., proteolysis which has been proven to play a role) need to be further investigated [ 8].

The generated formic acid proved to play a role as catalyst in main reactions.

Neural mechanisms are proved to play a role in the mechanism of allergic rhinitis symptoms.

Complement component 4 (C4) has be proved to play a role in pathogenesis of SLE.

Thus, ubp1 mutations may prove to play a role in multi-drug resistance, as is the case for mdr1 [ 43].

Several hormones and metabolic parameters have been proved to play a role in the relationship between energy balance and post partum reproductive efficiency in dairy cows.