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Unlike construction kits or computer games, both of which are almost exclusively marketed at boys and both of which have been proven to develop spatial skills and encourage creativity, most pink toys are prescriptive, unimaginative and unmalleable, concerning themselves with appearance or domesticity.
Teaching models and tools must be cost effective, adaptable to change, and proven to develop skills that transfer to clinical circumstances.
To increase the likelihood of detecting citrullinated proteins and the enzyme PAD4 in the joints of arthritic animals, we chose to perform the immunohistochemical stainings in the DA rat, because this strain has proven to develop the most severe CIA.
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In the RA study [ 14], antibody positive patients proved to develop more severe RA.
At the termination of the PCPT after 7 years, a total of 1,809 men were biopsy-proven to develop prostate cancer, and consisted the case pool for this nested case control study.
House-bots have actually proven to be harder to develop than expected.
Thus far, it has proven difficult to develop successful treatment strategies for diseases that are caused by mtDNA instability.
While implementing the transmitter side of such systems is relatively trivial, the receiver has proven challenging to develop.
"Phil has a proven ability to develop players while cultivating great team spirit, and a winning culture," said the WICB chief.
Spurs chairman Daniel Levy said: "He has a proven ability to develop each player as an individual, whilst building great team spirit and a winning mentality".
However, it has, thus far, proven difficult to develop delivery vehicles that increase the efficiency of gene delivery to hMSCs, due to several problematic issues.
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