Citrate has been proven to reduce complement activation in human blood and several studies have reported beneficial effects when replacing acetate- with citrate-containing dialysis fluid [ 13, 24, 35– 35].
Ms. Beeler's design and technical skills, as well as her natural attention to detail, order and planning have proven to be a formidable complement to her husband's artistic vision and methodical nature.
Keith Rabois joined as COO less than a year later in August 2010 and has proven to be an excellent complement while Square has grown explosively.
The applied strategy of time series data has proven to be a powerful complement to randomized nutritional studies adopting a clinical trial design.
Molecular vouchering is proved to efficiently complement morphological species identification in nematodes [ 73, 122, 124– 128].
Zebrafish has proven to be a useful vertebrate complement to the mouse [ 6].
Traditional serological biomarkers such as anti-dsDNA antibodies and complement levels have been proven to be neither reliable indicators of disease activity [ 1, 2] nor predictors of impending disease flares [ 3].
Once proven to be differentially expressed as serum proteins, it will need to be investigated whether a marker could complement mammography in early detection.
As a complement to the untargeted proteomics approaches, a targeted approach based on multiple reaction monitoring (MRM) has proven to be feasible for high-throughput proteomics studies [ 39].
Therefore, in the present work, we explored the architecture of disease relationships in terms of dysfunctional regulation mechanism by using DCEA for the first time, which has proved to be a complement to the disease networks generated from symptoms, disease concepts, biomedical big data.
