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In these cases effective chemotherapies have not been established and recent promising treatments have proven suboptimal [ 9- 12].
However, current standard response criteria have proven suboptimal for the assessment of the antiproliferative effect of many targeted agents, particularly in the context of slow-growing tumors such as well-differentiated NETs.
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Furthermore, when receive (SNR) increases, interferences become important and linear MMSE techniques prove suboptimal compared to SIC.
The effect of 1 mg is less consistent and a dose regimen of 0.5 mg once daily proved suboptimal in all studies.
Traditional insulin products have generally proven to be suboptimal with regards to providing a consistent level of hormone for maintaining metabolic balance over a 24-hour period, while at the same time limiting the development of adverse effects such as hypoglycemia.
However, suppression of time as a variable in the overall optimisation framework has proven to result in suboptimal results.
Having endured natural selection pressures from a variety of disease agents and harsh climatic conditions, Nguni cattle have proven to prevail in suboptimal environmental circumstances [ 8].
Despite increasing costs associated with asthma [ 2], care remains suboptimal, with many patients tolerating symptoms and lifestyle limitations unnecessarily, due to suboptimal use of proven available therapies [ 11, 26, 29, 32].
We tested several materials and found that a poly 3-hydroxybutyrate-co-3-hydroxyvalerate) (poly 3-hydroxybutyrate-co-3-hydroxyvalerateinocytes, although adhesion to this material poly 3-hydroxybutyrate-co-3-hydroxyvalerate
Clinicopathological predictors have proved to be suboptimal in identifying high-risk patients.
Identification of medical urgency during telephone contacts with GP cooperatives proved to be suboptimal [ 16- 18].
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