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With all the concern most parents express about the safety of their children, it is surprising -- no, shocking -- that so many parents are so casual about a proven safety measure that could make a life-or-death difference: the consistent use of proper child restraints in motor vehicles, especially for children who are too old for infant and child safety seats and too young for adult seat belts.
They have been widely used for the delivery of therapeutics and vaccines due to their proven safety, biocompatibility and ease of manufacturing (Torchilin, 2005).
Trains would also have to cover a long distance but Highland Council said taking nuclear material by rail had a proven safety record.
In one recent review of published studies on non-cancer pain, cannabinoids appeared to have proven safety and modest efficacy in the treatment of neuropathic pain whereas, there are some evidences of efficacy also in fibromyalgia and rheumatoid arthritis [19].
In an era of ever expanding health care costs, proven safety and effectiveness is not sufficient anymore to obtain funding, objective data about cost and cost-effectiveness are nowadays additionally requested.
This proven safety record does not absolve car manufacturers from their problems with recalling malfunctioning vehicles, nor does it absolve highway patrol officers from their misconduct and injustices.
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Long studies to prove safety and efficacy, which the brand-name manufacturers conduct to bring new drugs to market, are not necessary for the generic versions.
The regulatory guidelines would indicate how the drug rules would be interpreted for transgenic animals, and what types of data would be needed to prove safety and efficacy.
Emma Tuddenham, a spokeswoman for Colipa, a group representing the cosmetics industry, said: "All tests are performed to prove safety for human health, which is our top priority".
With the large number of deaths and the probability that far more were unreported, a stronger bill, demanding that companies must prove safety and effectiveness before their products could be sold, was introduced.
But Dr. Sidney M. Wolfe, director of Public Citizen's Health Research Group, a Washington advocacy organization that had petitioned the agency to regulate saline implants, said the studies conducted by McGhan and Mentor hardly prove safety and effectiveness.
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CEO of Professional Science Editing for Scientists @ prosciediting.com