Sentence examples for proven inactive from inspiring English sources

In addition, the cysteine protease inhibitor E64, an epoxysuccinyl peptide, has proven inactive against the NS2 autoprotease (Pieroni et al., 1997; Thibeault et al., 2001).

Although it has been predicted that this tRNAser gene (for AGN) may be a pseudogene as observed among other metazoan mitochondrial genomes and some of them were proven inactive [ 8], efforts have been made to uncover underlying molecular details as to how serine residues are actually added into peptide chains with this "bizarre" tRNA [ 9].

The (D --enantiomer proveD --enantiomerinst HIV-1 RT.

Granny Smith apple juice and orange juice proved inactive.

Moreover, by the functional assays 1 and 2 proved inactive at all α2-adrenoreceptors subtypes up to 10− 3 M.

Although the compounds ultimately proved inactive against HIV, during the course of the synthesis, a new and highly facile method to realize N-phenylacetamides was developed.

In vitro electrophysiological experiments on rat brain slices demonstrated that four of these peptides counteracted with the field excitatory postsynaptic potential-attenuating effect of Aβ1 42; only Arg-Val-Val-Ile-Ala amide proved inactive.

Of these, 6 proved inactive, suggesting a loss of transport activity.

Unfortunately, a large number of the NBD congeners that were designed and synthesized during the virtual screening program proved inactive.

SA-17 also inhibited YFV-17D replication, although less efficiently than DENV replication, but proved inactive against other viruses (the picornavirus coxsackievirus B3, the retroviruses HIV-1 and HIV-2, and the herpesvirus HSV-1).

The major breakdown product in vitro was identified as EO-5A which proved relatively inactive compared to EO-9 (IC50 = 50 and 0.6 ug ml-1 respectively).