Sentence examples for proven efficacy for from inspiring English sources

For example, tamoxifen has proven efficacy for reducing the incidence of primary and recurrent breast cancer but is also associated with an increased risk of endometrial cancer[ 52].

Both antimuscarinic agents and β3-adrenergic agonists have proven efficacy for reducing symptoms of urinary frequency, urgency and incontinence [ 46, 47].

Low-dose hydrocortisone can be added for patients not responding promptly to standard vasopressor therapy and has proven efficacy for reversal of refractory vasodilatory shock [ 88, 89, 118].

It has proven efficacy for the treatment of glabellar frown lines, 6, 7 and has been licensed for this indication widely throughout Europe as Bocouture®.

Several strategies have proven efficacy for preventing central line-associated blood stream infections (CLA-BSIs), but care bundle approaches seem to be the most prominent.

The pentasaccharide fondoparinux can be administered once daily subcutaneously in a fixed dose and has proven efficacy for the treatment and prophylaxis of venous thromboembolic manifestations [ 47, 48].

Currently, intravenous thrombolysis with tissue plasminogen activator (tPA) remains the only therapy that has proved efficacy for acute ischemic stroke.

Rotigotine also has proven efficacy as monotherapy for the management of moderate to severe idiopathic RLS, as demonstrated in two phase III, randomized, placebo-controlled trials [ 50, 60].

Capecitabine has proven efficacy as monotherapy for the treatment of patients with locally advanced or metastatic breast cancer (MBC) after failure of anthracycline- and taxane-containing chemotherapy, or in patients for whom further anthracycline therapy is not indicated.

However, empirical evidence shows that although double-blind randomized controlled trials are the gold standard for proving efficacy of a therapeutic procedure, they often suffer from lack of generalizability [26].

Since the 1970s, N-acetylcysteine (NAC) has shown proven efficacy as an antidote for acetaminophen (APAP) poisoning and APAP-induced liver failure for early presenters.