Sentence examples for proven deleterious from inspiring English sources

Endothelin receptor blockers, however, have been proven deleterious as a prophylactic tool against CIN [ 226].

However, endothelin Receptor Blockers have been proven deleterious as a prophylactic tool against contrast-induced AKI [ 196].

Hg has proven deleterious effects on male reproductive system that have been extensively investigated over the past years [ 9, 10].

To estimate which families with a UV have features similar to those with a proven deleterious mutation, we chose probands with neutral variants as negative controls.

In optimizing the human ACHE-S gene sequence, we took a preemptive approach: modifying many molecular features that might have otherwise proven deleterious to the expression of the transgene or to the accumulation of its product.

We have identified a combination of variables from the cancer history of the probands and their families that significantly distinguish families with proven deleterious variants from those with neutral variants, and we have used them to develop logistic regression models to classify individual UVs in the BRCA genes.

Hence, it is deduced that Pd/Pt electrocatalysts utilising Nafion membranes should not prove deleterious to electrocatalytic activity.

Finally, reversal of one of the central amide bonds as in series 13 proved deleterious to the inhibitory activity.

Many valuable compounds, or the intermediates necessary for their biosynthesis, prove deleterious at the desired production concentrations.

Introduction of a 17α-benzyl substituent to such 2-substituted estrogen sulfamates also proved deleterious to anti-proliferative activity but could, in one case, enhance STS inhibition with respect to the parent substituted estrone sulfamate.

Initially we were concerned that the silencing of this receptor might prove deleterious.