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Although there are promising data on the sensitivity of these newer screening methods, especially low-dose CT, for detecting early lung cancer, none of the published trials are controlled, and they have not yet proven a decrease in mortality.
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The conduct of a business in violation of a zoning ordinance creates a public nuisance, but it also may be actionable as a private nuisance by neighbours who can prove a decrease in the market value of their homes as a result.
The results of our study, as well as the studies by other authors, are unanimous in proving a decrease in the thermal expansion coefficient of aluminium containing nanotubes.
However, as the overall number of patients evaluated was small, the power of this study to prove a decrease in ECMO necessity was low (β error 10%).
Overexpression of miR-133a inhibited VSMCs transdifferentiation into osteoblast-like cells, as proven by a decrease in ALP activity, OC secretion, Runx2 expression, and mineralised nodule formation.
A phase 2 trial was completed and it proved a decrease of A β42 concentration in CSF and an improvement of cognitive and behavioral performance [ 90].
For example, genetic variants associated with increased low density lipoprotein cholesterol also increase the risk of cardiovascular disease and mortality in accordance with observational studies, 9 and randomised intervention trials have proved that a decrease in low density lipoprotein cholesterol reduces cardiovascular disease and all cause mortality.
However, as the interaction between CHEK2 and adjuvant chemotherapy is not significant, we cannot prove a decreased sensitivity to adjuvant chemotherapy in CHEK2 breast cancer patients.
The scopoletin/horseradish peroxidase method[23] allows for detection of low nM concentrations, but the need for standard additions and quantification via a decrease in fluorescence prove to be time consuming.
The only alteration found in donkeys proving positive for B. caballi was a decrease in PLT in one subject.
Moreover, eliminating reactive oxygen species in turn leads to a decrease in VEGF levels proving the specificity of oxidative stress reactions [ 78].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com