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Krek's report proved this principle [20] and our results further indicate that miRNAs with independent binding sites in a gene can produce coordinate action, which increases the repressive effect of miRNAs on translation of this gene.
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The molecule chosen to prove this principle was Retinoic acid (RA), which is known by its ability to induce many cellular changes in diverse cell types in vivo and in vitro [7] [11].
We also developed procedures for affinity ranking of protein ligand interactions from ligand-induced changes in chemical denaturation data, and proved the principle for this by correctly ranking the affinity of previously unreported peptide PDZ domain interactions.
This study has proved the principle that the whole-cell SELEX could be a promising technique to design aptamer-based molecular probes for dectection of pathogenic microorganisms without tedious isolation and purification of complex markers or targets.
In this study we proved the principle of LOFT in the context of T-cell development, at a hypomorphic allele of Baf57/Smarce1 encoding a subunit of the chromatin-remodeling Brg/Brahma-associated factor (BAF) complex.
The manner in which Dahal and Goodrich proved this result was by the principle of strong induction.
"We've proved the principle that from these embryonic stem cell lines we can generate red blood cells," Professor Turner said.
The l-arabinose biosensor presented in this study proves the principle of an outer membrane complex based sensing method which could be easily modified to different specificities by a simple change of the regulatory elements.
Therefore, this work proves the principle that cataract prevention can be achieved by promoting intercellular gap junction communication in the lens.
In this report, we prove the principle of ramification amplification.
"John and the Oregon Health Plan broke significant ground, proved the principles worked.
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