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That has proved problematic in this America's Cup, now the longest in history at 19 days, in part because of numerous postponements.
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This issue has proved problematic in the implementation of community responses to volcanism [80] and to the impacts of associated hazards [81, 82].
This last feature proved problematic in the extreme conditions of the Eastern Front.
The contract also repeats the "cost plus" arrangement that has proved problematic in the past.
Later that year came Whore, about the travails of a prostitute, whose very title proved problematic in the US.
However, this attempt to distinguish and segregate a technical-managerial approach to the functional agencies, as if a category of low politics could be kept separate from high politics, proved problematic in the later development of the functional agencies.
While treatment of fibroblasts derived from these mice with 4-hydroxy-tamoxifen could be used to generate talin1 null cells, the system proved problematic in that talin2 was rapidly upregulated (Fig. S1A), and the cells were still able to assemble paxillin-containing FAs (Fig. S1B).
Thankfully, given the B-movie premise, it's knowingly pitched, aiming to recapture the spirit of Gremlins as a film that kids might sneakily watch and then regret it when trying to sleep later (a particularly nightmarish child-eating clown should prove problematic in this instance).
Moreover, this hypothesis most adequately explains the anatomical details that have proved problematic in other hypotheses, such as the structure and carriage of the neck and skull and relatively small feet.
But that formulation has proved problematic in an economic downturn.
His stance immediately proved problematic in a city heavily in favor of abortion rights.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com