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Genotype cluster investigations proved particularly difficult in several situations.
(This proved particularly difficult in primary care - see below).
Community recruitment of drug users proved particularly difficult in Beijing – only 50 recruits over several months of effort.
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Unraveling the Mahdi Army has proven particularly difficult, in part because of the elaborate web of patronage and tribal systems that crisscrosses the closely knit neighborhood of Sadr City.
Efficient linguistic behaviour has proved particularly difficult to produce in a machine.
Dogs have proved particularly difficult to clone, in part because their oocytes mature only after they are released from the ovary and are difficult to culture in the lab.
Tuberculosis (TB) remains a major challenge to global public health and has proved particularly difficult to control in regions with high HIV prevalence.
Controlling the amount of this gas in air has proved particularly difficult for the UK.
Non-governmental organisations known in party-speak as "new social organisations"—have proved particularly difficult to penetrate.
And until the most recent gas attack in Syria, reliable assessments of the use of chemical weapons proved particularly difficult.
Crowd-sourcing has proved particularly difficult.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com