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In murine NIH3T3 fibroblasts, the chimeras showed immediate plasma membrane permeabilising properties, which proved highly dependent on the chimera chain length, and were remarkably different from the effects induced by Tat47 57.
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We anticipate that it will prove highly dependent on the relative efficiency of Antarctic phosphatase over T4 Polynucleotide Kinase, as the latter is part of the standard end-repair enzymatic cocktail used for library building and could also catalyse the removal of 3'-phosphoryl groups from polynucleotides.
Others unable to pass nonuniform test highly dependent on examiner and Location.
The impact of oxygen penetration proved to be highly dependent on the denitrification rate.
The energy performance of electrochromics proved to be highly dependent on how blinds were controlled.
In conclusion, the nature of surface hydrophobicity proved to be highly dependent on surface morphology as the base materials used are intrinsically hydrophilic.
Unfortunately, the effectiveness of small molecule inhibitors of EGFR such as gefitinib and erlotinib has been proved to be highly dependent on PI3K and PTEN status and yielded modest results [16].
Current sequence-based approaches to identify enzyme functional shifts, such as enzyme promiscuity, have proven to be highly dependent on a priori functional knowledge, hampering our ability to reconstruct evolutionary history behind these mechanisms.
That the afterlife is not only subjective but highly dependent on one's mood.
The reaction of symmetric ketones 7– 11 with 1 proved to be very complex and highly dependent on the acetylene termini (Scheme 3 and Table 2).
Although we do not exclude that also other MMP13 substrates play a role in the observed LPS resistance, we proved that the observed phenotype is highly dependent on TNF activity.
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