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Citicoline is the only neuroprotectant that has proved efficacy in patients with moderate to severe stroke.
If a given method proved efficacy in the chronic state, follow-up studies may broaden the indication to severely disabling episodic states, if medically not sufficiently treatable.
All of them proved efficacy in glycemic control with impressive safety and tolerance profiles [ 26].
Simvastatin has proved efficacy [ 12- 14, 23] and is the cheapest statin in Sweden.
Currently, intravenous thrombolysis with tissue plasminogen activator (tPA) remains the only therapy that has proved efficacy for acute ischemic stroke.
We classified interventions without proved efficacy according to the Picard review, and new, potentially useful interventions that had not yet been retrieved in that systematic review, as experimental interventions.
Similar(49)
Sorafenib has proven efficacy in metastatic renal cell carcinoma (mRCC).
The first-generation (nicardipine) agents have proven efficacy against hypertension.
The Flutter Valve (Varioraw SARL, Scandipharm Inc, Birmingham, AL) has proven efficacy in hypersecretive spontaneously ventilated patients.
Failure to prove efficacy, safety and quality control would not prevent the widespread use of homeopathy in home remedies, but it could lead to restrictions on professional practice.
Although drug companies are willing and ready to pay for randomized controlled trials to prove efficacy, it's not clear who is going to finance studies like these.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com