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In terms of efficacy (secondary objective), esomeprazole proved efficacious in preventing the recurrence of peptic ulcers in this at-risk patient population, with an overall estimated ulcer-free rate after 1 year of 95.9%.
On March 7, Guidant announced that it was suspending its clinical trials of stents coated with actinomycin-D, because that drug has not proved efficacious in preventing restenosis.
Thus, C. asiatica by acting as a potent antioxidant exerted significant neuroprotective effect and proved efficacious in protecting rat brain against age related oxidative damage.
Virtual surgical planning (VSP) with subsequent computer-aided design and manufacturing have proved efficacious in improving the efficiency and outcomes of a plethora of surgical modalities, including mandibular reconstruction and orthognathic surgery.
Feeding diets with 10 ppm RAC to pigs with ending BW of approximately 147 kg proved efficacious in improving BW, ADG, G F, HCW, and dressing percentage without adversely affecting meat quality traits.
Corroborating a preliminary report [20], the IgG mAb proved efficacious in reducing fungal growth as early as after a 4 h contact and in a dose-dependent manner.
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Topiramate has also proven efficacious in patients with chronic migraine [47, 48].
Many of these strategies have proven efficacious in the short term, but less successful in long-term weight loss and maintenance of that weight loss.
Although a few of them have shown limited efficiency in animal models or in small clinical studies, none of the currently available antioxidants have proven efficacious in a large-scale controlled study.
We posit that knockdown of Bmi-1 will prove efficacious in combination therapy with this regimen.
This has proven efficacious in preclinical models [48], and will be tested clinically by Merck and Astrazeneca in the near future (NCT01021748: MK2206 and AZD6244 for solid tumors).
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