Such transgenes have proven effective at improving OV therapies, and basic research has shown mechanisms of p53-mediated enhancement of OV therapy, provided optimized p53 transgenes, explored drug-OV combinational treatments, and challenged canonical roles for p53 in virus-host interactions and tumor suppression.
Lessons relayed through theater productions, walking initiatives, and the empowerment of youth leaders have proven effective at improving physical activity levels, educating youth on healthy eating habits and helping them confront body-image and other age-sensitive issues.
The contraceptive, which began to be used at a management level in 1995 although it was used in smaller amounts as early as 1989, has also proven effective at improving the health and increasing the life expectancy of older mares through the removal of pregnancy and lactation-related stress.
Other interventions testing single or multiple components have also proven effective at improving ECND outcomes.
Indeed, this model has proven effective at improving the outcomes of all-cause CKD patients in BC.
While technology proceeds in fits and starts, several low-tech measures have proven effective at improving colonoscopy performance.
Generally speaking, 78.67% of projects in 2006 and 78.32% of those in 2007 proved effective at either improving or stabilizing productivity; however, only 40.56% and 34.34%, respectfully, were effective at doing both.
Active immunization, in which mice were inoculated with tau peptides, also proved effective at preventing and improving tau pathology in mice overexpressing human P301L tau [ 62].
Representative democracy has proved effective at staving off class war.
The stopwatch proved effective at reducing the time it takes children to buckle their seat belts.
