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In fact, Khan's enterprise — dispersed, diverse, and in some respects politically protected — has proved difficult to untangle.
However, despite ample evidence of benefit, the complex phenomenon of social participation has proved difficult to untangle in creating policies or programs for optimizing health in diverse communities.
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Even if regulators gain new powers to curb the use of consultants, their ties to the firms may prove difficult to untangle.
Complex relationships between many different species of organisms characterize the biological world, but the details of these symbiotic relationships have proven difficult to untangle through reductionist experimentation.
Although epidemiologic evidence tends to support that hypothesis, it has proven difficult to untangle the complex web of exposure effects, stressors, and mechanisms behind the potential differences in susceptibility.
The direction of causation might prove difficult to untangle, particularly where specific symptoms are tightly clustered.
Genocide has proved difficult to prosecute.
The effect proved difficult to measure.
The latter aim proved difficult to enforce.
Spectacular early results proved difficult to sustain.
Neutrality proved difficult to maintain, though.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com