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The UN system has also relied on legally binding agreements, which sound good in theory yet have proved difficult to tailor and adjust in light of the many different interests that must be reflected in any serious international pact to control emissions.
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A close fit between the defect site and the artificial bone substrate is important for improving bone healing and stress transduction [ 4], but it has proven difficult to tailor ceramic scaffolds to fit specific defects.
Genocide has proved difficult to prosecute.
The effect proved difficult to measure.
Neutrality proved difficult to maintain, though.
Alas, it proved difficult to find.
Spectacular early results proved difficult to sustain.
The latter aim proved difficult to enforce.
Yet reform proved difficult to implement.
The furlough plan proved difficult to enforce.
The advice proved difficult to follow.
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