Sentence examples for proved difficult to align from inspiring English sources
These outgroups were chosen because the S. cerevisiae sequence (NHA1) most similar to the plant SOS1 genes proved difficult to align with the rest of the plant genes.
Where highly divergent nucleotide sequences proved difficult to align, sequences were converted to amino acids and aligned by eye and back translated to nucleotide in SE-AL [ 59].
One portion of each of the non-coding regions psbA-trnH, trnL-F and trnS-trnG proved difficult to align, either automatically via software or manually.
We imposed lower and upper limits on intron lengths because indels in extremely short introns may not be neutral and extremely long introns might prove difficult to align.
The latter aim proved difficult to enforce.
Genocide has proved difficult to prosecute.
The effect proved difficult to measure.
Spectacular early results proved difficult to sustain.
Yet reform proved difficult to implement.
The advice proved difficult to follow.
Neutrality proved difficult to maintain, though.
