To prove stage-specific activity of the promoter, GFP and luciferase reporter assays have been successfully established, allowing both qualitative and accurate quantitative analysis.
The Hammersmith data consisted of 13 [18F]FLT PET scans of patients with histologically proven stage II-IV breast cancer based on American Joint Committee on Cancer stage (AJCC) criteria.
Inclusion criteria were cyto-histologically proven stage IIIB-IV NSCLC; age of 70 years or less; Eastern Cooperative Oncology Group (ECOG) perfomance status of 2 or less; normal cardiac, hepatic, renal and bone marrow functions; and no previous chemotherapy.
The F-18-FDG PET/CT scans of the first 35 consecutive patients with pathologically proven stage IIB-IIIB (American Joint Committee on Cancer Staging), in-operable NSCLC enrolled in a national phase II trial were evaluated.
Addition of bran at 15% substitution decreased loaf volume further and also decreased the maximum expansion during proving, indicating that at this level bran exerts at least part of its effect in reducing loaf volumes during the proving stage of the breadmaking process.
Perhaps the junior partners I spoke of earlier were still in the "proving" stage and couldn't risk a status downgrade by associating with a staff attorney.
We included 42 patients with histological or cytological proven stage IIIa-N2 or IIIb NSCLC.
Patients with histologically proven stage Ib-IVa (AJCC 6th edition) gastric adenocarcinoma are eligible for this study.
A total of 154 patients with histologically proven stage III adenocarcinomas were selected as previously described [ 16, 17].
In all, 55 patients had pathologically proven stage IIIa-N2 NSCLC, by mediastinoscopy (33), EUS-FNA (16), thoracotomy (4) and bronchoscopy with TBNA (2).
Locally advanced NSCLC patients with histopathologically (by bronchoscopy and mediastinoscopy) proven stage IIIA (N2), and selected patients with stage IIIB or oligometastatic stage IV (single metastasis, e.g., in adrenal glands) were included.
