The biological basis of this link is likely to be multi-factorial including both age-associated decline in anti-oncogenic functions, such as repair of oxidative damage to DNA, timing of etiologic exposures and/or protracted time required for accumulation of a full set of oncogenic mutations [ 1, 2].
Ever since my sister's death, I've been convinced that any protracted time spent with a health-care professional is a prelude to terminal illness.
The protracted "time to build" means that if property prices shoot up, only the builders who started work years ago benefit.
If we have a very protracted time when companies are strapped for cash, they may decide not to use outplacement services.
Only a handful of city governments of the developed and developing world have control over their metropolitan area, reflecting different institutional arrangements and the protracted time-lag required to align urban growth "on the ground" with political boundaries.
Moreover, a number of trends are converging to act as protracted time bombs: water is increasingly scarce, a problem exacerbated by climate change; the region is already the biggest grain importer in the world; and the demographic bulge is swelling by the year.
The TIPS method eliminates the need and protracted time for titering virus supernatants, and provides stable, concentrated storage of recombinant baculovirus in the form of infected cells.
Citing work on the Mueller-Lyer illusion, Fodor (1983) argues that modularity is consistent with the possibility that cultural settings can, over protracted time periods, alter how information is processed.
Rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are disorders characterised by excessive production of proinflammatory cytokines, including tumour necrosis factor-α (TNF), and patients with these chronic diseases receive treatment for a protracted time.
