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The biological basis of this link is likely to be multi-factorial including both age-associated decline in anti-oncogenic functions, such as repair of oxidative damage to DNA, timing of etiologic exposures and/or protracted time required for accumulation of a full set of oncogenic mutations [ 1, 2].
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Only a handful of city governments of the developed and developing world have control over their metropolitan area, reflecting different institutional arrangements and the protracted time-lag required to align urban growth "on the ground" with political boundaries.
The TIPS method eliminates the need and protracted time for titering virus supernatants, and provides stable, concentrated storage of recombinant baculovirus in the form of infected cells.
"The savings we achieved go a long way toward insulating the project from any dip in rents or any protracted period of time required to lease up the building," she said.
Dispossessed pastoralists generally reconstitute herds only in the long term, which may be compared with the time required for refugees living in protracted situations to regain their subsistence strategies and cultural identity (Khalif and Oba [2013]; McCabe [1987]).
It is also likely that regions showing signals associated with response checking will show a more protracted timecourse of response than will regions that reflect pathway control, owing to the time required to complete a decision-making process.
In practice, however, the conservative and risk aversive culture of ethical review means that the procedures required to obtain such permissions are complex and protracted to the extent of deterring all but the most determined researcher, and perhaps the few who have unlimited time required to pursue the endeavour [ 11, 19, 45, 69].
Achieving results in fragile contexts and protracted crises requires more time and more resources than in stable settings, and at a greater risk.
It is argued that in a presidential system a protracted process is required.
The protracted alternative requires many assumptions, does not account for legume biology, fails to distinguish domestication from postdomestication changes, and, therefore, is less parsimonious.
*The recommended antibiotic, ciprofloxacin, is taken for a protracted time, perhaps 45 to 60 days.
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