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We observed that both the Δyca1 and C297A strains had a protracted progression through the cell cycle suggesting that endogenous expression of Yca1p improves robustness of yeast cells in fermentive conditions (Fig. 2 b).
Interestingly, the C297A strain also demonstrated a protracted progression through S phase when compared to both the BY4741 and Δyca1 strains.
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Conversely, there is mounting clinical evidence suggesting an association between increased levels of serpin expression and reduced incidence of HIV acquisition, or protracted disease progression [18], [19], [20].
Given the often protracted nature of kidney disease progression, nephrology providers may need to employ skills in these areas repeatedly over time.
Seal The rubber-stamping of a transfer deal (protracted or otherwise) or the relatively untroubled progression of a club to the next round of a cup competition.
The disease course is also variable, ranging from patients who remain stable for protracted periods of time to others whom experience rapid stepwise progression with accelerated mortality [11] [13].
After progression, patients will be followed every 3 months for disease status, protracted toxicities, further treatment, and survival.
Consequently, factors such as better performance status are likely to indicate those patients who are likely to have more prolonged progression-free survival and who may therefore receive chemotherapy for more protracted periods of time (Borner et al, 1998).
A protracted silence.
They are also protracted.
Conflicts are becoming more protracted.
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