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They have been protracted and hugely complex.
One mechanism that has been proposed to explain the schedule-dependent anticancer activity of temozolomide, as well as the encouraging, although preliminary, results noted with protracted low-dose schedules, is that frequent temozolomide treatment, particularly on protracted schedules, may lead to marked, cumulative, and sustained inactivation of O-alkylguanine-DNA alkyltransferase (AGAT).
The conflict could be protracted and bloody.
This struggle was protracted and fierce.
Scenes of torture are protracted and inventive.
That makes appeals against extradition protracted and expensive.
Production was protracted and reviews none too positive.
Patients requiring prolonged mechanical ventilation (PMV) and protracted and weaning after critical illness is rising.
The whole affair was protracted and the atmosphere vicious.
Audience response was rousing and sustained.
The applause was raucous and sustained.
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CEO of Professional Science Editing for Scientists @ prosciediting.com