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Despite the suppression of hydrolytic activities observed in early phagosomes, late phagosomes exhibit an enhanced and protracted accumulation of lysosomal cargo.
In Barb the rates of synonymous and non-synonymous substitutions approached unity (Ks/Ka = 1.03 ± 0.12), which is consistent with the protracted accumulation of mutations in a solely neutral mode.
Exposure of exponentially growing NHFs to UVc radiation (20 J m 2) or γ radiation (2.5 8 Gy) led to a 45 60% inhibition of proliferation and protracted accumulation of cells in the G2/M phase.
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The protracted data collection period was due to logistics challenges.
With steady accumulation over protracted periods of time, such deposits tend to become very thick and subside under their own weight, forming troughlike structures parallel to their sediment source.
The biological basis of this link is likely to be multi-factorial including both age-associated decline in anti-oncogenic functions, such as repair of oxidative damage to DNA, timing of etiologic exposures and/or protracted time required for accumulation of a full set of oncogenic mutations [ 1, 2].
We show that A2E triggered the accumulation of debris followed by a protracted death.
44 This protracted rate of elimination accounts for the magnitude of accumulation observed with terbinafine after repeated dosing and the persistence in plasma and tissues long after discontinuation of the drug.
Factors involved in the accumulation of monocytes in CSF of SRMA patients during the protracted form have not been investigated.
All it takes to grease the skids is a steep decline in the stock market (both Tom Wolfe's "The Bonfire of the Vanities" and Oliver Stone's "Wall Street" took off in post-crash '87) and an ugly, protracted battle between the Government and a corporation synonymous with the era's accumulation of money and power (Drexel then, Microsoft now).
A protracted silence.
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CEO of Professional Science Editing for Scientists @ prosciediting.com