In a previous report we show the ability to simulate the SE response of prototypical samples based on far-field projections of near-field simulation based on the FDTD method with accuracy equivalent to ∼0.5 monolayer precision in film thickness up to 70° angle of incidence (AoI).
Importantly, the patient specimens tested herein were collected in a remote region of Iran, and therefore represent the prototypical samples that would be evaluated in the field with the Global Focus microscope.
The R package SigClust was used to assess significance of each cluster in order to identify the prototypical samples that were used to derive the centroids.
We will call these regions "clusters", and we will introduce a method how to sample prototypical filters from the clusters, using a notion of "inlier" points which have a low distance to their nearest neighbors [20], [21].
Our method mostly misclassified prototypical HER2-enriched samples.
A general study of performance attributes was conducted for a prototypical electrothermal vaporization (ETV) sample introduction system, in which induction heating (IH) was used to facilitate the drying, pyrolysis, and vaporization of samples from long, undercut graphite cup probes in a radio-frequency (RF) induction field.
A prototypical description of this sample would be a man in his late 30s who has completed secondary school, possibly employed and seeking treatment.
Briefly, each user extracted RNA from three FFPE breast tumor tissue samples to demonstrate proficiency in tissue processing, and each user processed four prototypical breast tumor RNA samples (one of each intrinsic subtype with known expected ROR score values) along with a negative control sample to demonstrate proficiency on the nCounter Analysis System.
Hepatocytes were then treated for 24 h with these medium samples or prototypical inducers [3-methycholanthrene (3MC),rifampicin (RIF) or phenobarbital (PB)] under standard conditions and CYP1A1/2, 2B6 and 3A4 mRNA levels were measured (Fig. 5).
We excluded these tumor-like normal samples in developing a prototypical normal contamination profile and used 48 normal-like samples to calculate median gene expression.
