Sentence examples for prototype compounds for from inspiring English sources

The use of nanoparticle parenteral drug delivery systems for oral, IV injection and IV infusion of tool compounds to reach desired exposures allows researchers to obtain reliable and critical data for early decision making early in the discovery process without large investment by utilizing less-than-ideal, prototype compounds for target validation.

Doxorubicin and daunorubicin together can be thought of as prototype compounds for the anthracyclines.

IQ-FdUrd is potentially a prototype compound for new class of radiation-activated antitumor prodrugs that are useful for radiation treatment of hypoxic tumors.

Of note, widely variable responses to opioids have been reported between rats and mice, and species differences have gained relevance for predictive validity since prototype compounds with demonstrated analgesic efficacy in rodents have often failed in humans (Mogil, 2009).

The crystalline structures of selected prototype compounds have been solved.

Compared to the prototype compound 2, they had less cytotoxicity for Vero cells and less hemolytic activity for human erythrocytes.

The high potency and specificity of this drug makes it a prototype compound and a very useful tool for studying the effects of HDACIs.

A prototype Compound Parabolic Concentrating (CPC) solar energy collector for a sorption refrigerator has been designed, built and tested in laboratory at Warwick University.

The pan-caspase inhibitor z-VAD.fmk is a prototype compound that has been used extensively in vitro and in animal models for proof-of-concept studies.

The prototype compound, (R -N- sec-butyl -4- 2-chlorophenyl -N-11C-methyl-2-naphthamide [(R -N- sec-butyl -4- 2-chlorophenyl -N-11C-methyl-2-naphthamideging TSPO expR -N- sec-butyl -4- 2-chlorophenyl -N-11C-methyl-2-naphthamide

21 The prototype compound aliskiren is a small-molecular-weight, orally active, non-peptide that has high affinity for the active site on the renin molecule.