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Institutional use of transfusion protocols was associated with more restrictive practices.
We found that use of weaning protocols was associated with significant reductions in geometric mean values of 25% for the total duration of mechanical ventilation; 78% for weaning duration; and 10% for length of stay in intensive care.
Taking into account the total number of patients recruited annually, treatment of patients on clinical trial protocols was associated with considerable cost savings across both the non-commercial and commercial portfolio.
Analysis of the data by hierarchical clustering revealed that reduction in cell proliferation rate, which occurred with several of the treatment protocols, was associated with alteration in expression levels of a specific set of genes involved in cell-cycle progression, including MCM2, MCM3, MCM6 (cyclin B), and Ki-67.
A training and accreditation programme in customised fetal growth assessment with evidence-based protocols was associated with a reduction in stillbirths in high-uptake areas and resulted in a national drop in stillbirth rates to their lowest level in 20 years.
The use of institutional transfusion protocols was associated with more restrictive thresholds, especially in grade 1 SAH patients (mean Hb with transfusion protocol, 7.70 g/dL (95% CI, 7.54 to 7.87); mean Hb without protocol, 7.98 g/dL (95% CI, 7.80 to 8.16); P = 0.01).
Similar(54)
Both protocols are associated with benefits and challenges, and physicians must consider the needs of the individual patient when determining the best treatment options.
The importance of treating cancer-associated symptoms has recently been highlighted to oncologists with evidence that that the administration of routine chemotherapy protocols are associated with a significant 30-day mortality (NCEPOD, Systemic Anti-Cancer Therapy: For better, for worse?; http://www.ncepod.org.uk/2008sact.htm).htm
Nurse staff patterns and the implementation of clinical protocols were associated with mortality in septic patients and are potential targets to improve care of these patients in emerging countries.
Furthermore, these protocols are associated with costs that may not be covered by insurance.
Both protocols were associated with decreased fluid administration and maintained hemodynamic stability.
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