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Physicians should be aware that deviating from recommended protocols is associated with a higher rate of treatment failure and relapse.
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Both protocols are associated with benefits and challenges, and physicians must consider the needs of the individual patient when determining the best treatment options.
The importance of treating cancer-associated symptoms has recently been highlighted to oncologists with evidence that that the administration of routine chemotherapy protocols are associated with a significant 30-day mortality (NCEPOD, Systemic Anti-Cancer Therapy: For better, for worse?; http://www.ncepod.org.uk/2008sact.htm).htm
Nurse staff patterns and the implementation of clinical protocols were associated with mortality in septic patients and are potential targets to improve care of these patients in emerging countries.
Furthermore, these protocols are associated with costs that may not be covered by insurance.
Institutional use of transfusion protocols was associated with more restrictive practices.
Both protocols were associated with decreased fluid administration and maintained hemodynamic stability.
Goal-oriented protocols are associated with reduction of cardiac arrests in potential donors.
Unfortunately, some studies have concluded that the accelerated VIT protocols are associated with a significant increase in the incidence of systemic reactions compared with conventional protocols.
On an average, non-commercial trial protocols were associated with a small per patient excess treatment cost, whereas commercial trials were associated with a substantially higher cost saving.
On the other hand, minimization protocols are associated with progression of fibrosis, and noncompliance with the immunosuppressive regime constitutes a major risk factor for chronic humoral rejection.
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