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This requires development of expressive, high-level languages that allow reusability of protocols, characterization of their reliability, and a change in focus from implementation details to functional properties.
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The recent increase in feature density and lowered cost associated with the use of microarrays has prompted several groups to develop whole-genome based protocols for characterization of eukaryotic genomic content [ 15, 16].
Details of the synthetic protocols and characterization data for novel compounds can be found in the Supporting Information along with details of the biological methods used to evaluate these compounds.
The most commonly used protocols for characterization of GM events rely on anchor-PCR followed DNA sequencing of amplified products [ 21, 22], see also [ 23] and the sequences detected by our method should be sufficient for initiating a more detailed study using these standard approaches.
Our synthetic protocol and characterization followed earlier studies.
We previously published a detailed synthesis protocol and characterization of our micropatterned culture substrates.
The synthesis protocol and characterization of AcPhos SAMMS were published elsewhere (Birnbaum et al. 2002; Yantasee et al. 2003).
In 2003, a clinical protocol for characterization of patients undergoing orthopedic surgery and hand surgery was established at the Department of Rheumatology in Lund.
While molecular test results are less subjective than those from traditional microbiological/biochemical characterization protocols, it would be premature to advocate replacement of the traditional culture protocols at this juncture with molecular technology.
Furthermore, the method offers insight into optimal design of titration protocols for micelle characterization.
By combining nanodiscs and cell-free expression technologies, even completely detergent-free membrane protein characterization protocols can be designed.
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