The ethical Institutional Review Board has approved the study protocol and all the experiments were performed following the proper guidelines.
All the reactions were performed following the product protocol, and all the Entry clones and Expression clones have been sequenced.
The local ethic committees (National Public Health Institute, Karolinska Institutet, and University of Umeå) approved the study protocol, and all the participants signed an informed consent after the protocol had been fully explained.
The study protocol and all the amendments were approved by the Institutional Review Board or Independent Ethics Committee (core: NCT01259492; extension: NCT01338818).
However, this technical team reviewed the protocol and all the tools, gave comments and approved them.
The Institutional Review Board of Ruijin Hospital, Shanghai Jiao-Tong Universithestudyl of Medicine, aprotocolthe study protocol, and all the participants gave written informed consent.
The Ethical Committee of the Northern Ostrobothnia Hospital District, Oulu, Finland, approved the protocol, and all the patients gave informed consent.
The study protocol and all the questionnaires have been approved by the corresponding Institutional Review Boards of the Noor Vision Correction Center and the National Medical Research Center of Iran.
The experimental protocol and all the procedures used in this study were approved by the Animal Ethics Committee of the University of Padova, Italy (CEASA, approval number 73/2012).
The ethical committee of the Queen Fabiola Children's University Hospital of Brussels approved (on 20 September 2011) the study protocol and all the documents distributed to the schools, children and parents (reference: CEH-N°58/11).
