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The protocol synopsis for this trial and supporting CONSORT checklist are available as supporting information; see Checklist S1 and Protocol S1.
The study design process starts with a series of meetings, through which the feasibility study team decides the main objectives of the study and produces an initial study draft, called protocol synopsis.
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Relevant information that was labelled differently or found in other protocol sections or in a synopsis was also considered pertinent.
A synopsis of the study protocol is given as additional file 2. This study protocol presents a randomized controlled trial for a population of in-patients with serious, therapy resistant bipolar depressions.
Each project will be introduced by outlining the rationale, the questions the study will attempt to clarify, and a synopsis of the study protocol.
The synopsis for this systematic review protocol is registered in the International Prospective Register of Systematic Reviews (http://www.crd.york.ac.uk/PROSPERO), 12 registration number CRD42014010141.
To describe the external development of embryonic series I suggest the following protocol: Ordering: Primarily, specimens should be ordered by a comparative synopsis of the embryos' age and the development of reference organs, such as the number of somites, or as often used, the limb bud development [78] [79].
PCR protocols and primer sequences are available upon request, and a synopsis of the 15 variants is shown in Table S1.
Choosing who receives ECMO treatment is outlined in ELSO protocols, but there are many considerations that must be weighed as indicated in this synopsis.
On the basis of results gained from investigations covering periods longer than continuous records, a protocol embracing palaeohydrological inputs for application to river channel management is illustrated and developed as a synopsis version (Table 4), demonstrating how conclusions from geomorphological research can be expressed in a format which can be considered by managers.
The full methodology and a priori protocols governing the identification of studies and effect estimates for our systematic review have been described previously, but a synopsis is provided below.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com