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The most promising results seem to be achievable when using non-enhanced T1w/T2w and USPIO-enhanced T2*w sequences in combination with a dedicated axillary protocol (sensitivity 84.7 % and NPV 95.0%%).
To summarise, the most promising results seem to be achievable when using non-enhanced T1w/T2w and USPIO-enhanced T2*w sequences in combination with a dedicated axillary protocol, sensitivity 84.7 % and NPV 95.0%%.
The protocol sensitivity presented is the average of the three percentages obtained.
For this set of genes and the standard nCounter protocol, sensitivity and precision were comparable between the two platforms.
We exceeded our estimated sample size for the intention to treat analysis, though not for the per protocol sensitivity analysis.
We were also unable to perform a per protocol sensitivity analysis of the anti-fracture efficacy of alendronate in men who were compliant with therapy as these data were not published in the primary trials.
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These results demonstrate that the reporter tag of the substrate probe is critical for protocol execution, sensitivity, and dynamic range of enzyme activity assays.
cAMP levels were determined in triplicate from the cell lysates with a cAMP direct immunoassay kit (Calbiochem, San Diego, CA) following the manufacturer's protocol.he sensitivity of the assay was 0.39 pmol/ml.
The present report focuses on the implementation and validation of the protocol; its sensitivity as compared to previous methods is shown by RACE PCR on a range of transcripts.
Excluding patients who were not treated according to the protocol, the sensitivity became 74.1% (60/81) and the specificity 64.9% (161/248).
This review followed a predefined protocol, with sensitivity analyses arranged to answer specific questions that surfaced during study conception.
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