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Exact(18)
Superposition of all 6 independently refined monomers of Pfu-SRP19 show that the protein with the exception of the disordered loop L2 between the strands β2 and β3 is a rigid and compact structure (Figure 9A).
The remaining lumen protein genes, which showed a lower degree of co-expression with the genes in the above mentioned cluster but a high degree of co-expression among themselves (genes to the right of the gene encoding the 18.3 kDa protein with the exception of the gene coding minor plastocyanin (PLAS) in figure 3), were used in the same way to identify novel lumen related proteins.
The majority of sites under selection are in the TM regions of the protein, with the exception of TM3.
The status of RNA expression was variable, but the levels of Axin expression were equivalent to those of Axin protein with the exception of the TE8 cell line.
These missense mutations are rather equally distributed throughout the ABCD1 protein with the exception of three regions that are devoid of disease-causing mutations.
All mutations so far reported are missense changes, all are located in the M41-protease domain of the AFG3L2 protein with the exception of one (p.Asn432Thr) [ 3- 5].
Similar(42)
The amino acid sequences deduced from these gene sequences were characterized with the typical structure of α- or γ-gliadin or LMW- m type proteins with the exception of Gli-Ma2.
SUB1A-1 and SUB1A-2 encode identical proteins, with the exception of Ser186 in the tolerant allele and Pro186 in the intolerant allele.
In the present study, plasma total protein and albumin were significantly reduced in the EAAD and PF groups in comparison with the control, suggesting a malfunctioning of the liver in these groups (Table 6), since all the plasma proteins with the exception of immunoglobulins are synthesized in this organ (Rosalki and Mcintyre 1999).
The corresponding proteins with the exception of SCO5032 did not display such strong correlations.
All mutated proteins, with the exception of MMP-2 C233A, showed MMP-2 activity.
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